Comparative study of Antiplatelet Aggregation Activity of Bacopa monnieri extracted using Microwave and Ultrasonication

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of antiinflammatory drugs because of their natural origin. The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical extraction methods. Extracts of B. monnieri were prepared using different methods such as the Conventional organic solvent extraction method, Microwave Assisted Extraction (MAE) and the Ultrasonication Assisted Extraction (UAE) method. The efficiency of the extraction methods were studied by determining antiinflammatory activity by the in vitro antiplatelet aggregation method. The study revealed a 48.41 % and 45.68 % increase in activity for the extracts prepared using ultrasonication and microwave assisted extraction establishing their superiority compared to the conventional organic solvent extraction method.